Reading
Sources
The published sources this course outline is based on.
Sources
- Clinical and Laboratory Standards Institute. EP28: Defining, establishing, and verifying reference intervals in the clinical laboratory.
- Ozarda Y. Reference intervals: current status, recent developments and future considerations. Biochem Med (Zagreb). 2016;26(1):5-16.
- Fraser CG. Reference change values. Clin Chem Lab Med. 2012;50(5):807-812.
- Plebani M. Errors in clinical laboratories or errors in laboratory medicine? Clin Chem Lab Med. 2006;44(6):750-759.
- Justice JN, Ferrucci L, Newman AB, et al. A framework for selection of blood-based biomarkers for geroscience-guided clinical trials. GeroScience. 2018;40(5-6):419-436.
Evidence gap. No guideline defines "optimal ranges" distinct from reference intervals. Any optimal range used in practice should be stated as clinic policy, not as established evidence.